- 产品信息
商品描述
靶点-Target
Beclin 1
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
52kD
MW(Observed)
60kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0506R
特异性
Endogenous
基因名称
BECN1 GT197
蛋白名称
Beclin-1 (Ser15)
别名
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
Organism-1
Human
基因ID-1
8678
SwissProt-1
Q14457
Organism-2
Mouse
基因ID-2
56208
SwissProt-2
O88597
Organism-3
Rat
基因ID-3
114558
SwissProt-3
Q91XJ1
背景
beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
细胞定位
Cytoplasm





