FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
S100B
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
11kD
MW(Observed)
11kD
推荐稀释比
IHC 1:400-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0461R
特异性
Endogenous
基因名称
S100B
别名
NEF；Protein S100 B；Protein S100-B；S 100 calcium binding protein beta chain；S 100 protein beta chain；S-100 protein beta chain；S-100 protein subunit beta；S100；S100 calcium binding protein beta (neural)；S100 calcium-binding protein B；S100 protein beta chain；S100B；S100B_HUMAN；S100beta
Organism-1
Human
基因ID-1
6285
SwissProt-1
P04271
Organism-2
Mouse
SwissProt-2
P50114
背景
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy
细胞定位
Cytoplasm, Nucleus
