- 产品信息
商品描述
靶点-Target
RIP3
反应性
Mouse
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
50kD
MW(Observed)
50kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0528R
特异性
Endogenous
基因名称
RIPK3 RIP3
蛋白名称
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Organism-1
Human
基因ID-1
11035
SwissProt-1
Q9Y572
Organism-2
Mouse
SwissProt-2
Q9QZL0
Organism-3
Rat
SwissProt-3
Q9Z2P5
背景
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Nucleus





