FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MEK-4
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
44kD
MW(Observed)
44kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0589R
特异性
Endogenous
基因名称
MAP2K4
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 4
别名
MAP2K4;JNKK1;MEK4;MKK4;PRKMK4;SEK1;SERK1;SKK1;Dual specificity mitogen-activated protein kinase kinase 4;MAP kinase kinase 4;MAPKK 4;JNK-activating kinase 1;MAPK/ERK kinase 4;MEK 4;SAPK/ERK kinase 1;SEK1;Stress-activated pro
Organism-1
Human
基因ID-1
6416
SwissProt-1
P45985
Organism-2
Mouse
基因ID-2
26398
SwissProt-2
P47809
背景
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Cytoplasm, Nucleus
