- 产品信息
商品描述
靶点-Target
LKB1
反应性
Human,Mouse,Rat,
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
49kD
MW(Observed)
60kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0574R
特异性
Endogenous
基因名称
STK11
蛋白名称
Serine/threonine-protein kinase STK11
别名
STK11;LKB1;PJS;Serine/threonine-protein kinase STK11;Liver kinase B1;LKB1;hLKB1;Renal carcinoma antigen NY-REN-19
Organism-1
Human
基因ID-1
6794
SwissProt-1
Q15831
Organism-2
Mouse
基因ID-2
20869
SwissProt-2
Q9WTK7
背景
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Nucleus





