- 产品信息
商品描述
靶点-Target
Rpb1
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA,CHIP,Cut&Tag
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
192kD
MW(Observed)
250kD
推荐稀释比
IHC 1:50-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;CHIP 1:50-1:100;Cut&Tag 1:50-1:100;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0570R
特异性
Endogenous
基因名称
POLR2A
蛋白名称
DNA-directed RNA polymerase II subunit RPB1
别名
POLR2A;POLR2;DNA-directed RNA polymerase II subunit RPB1;RNA polymerase II subunit B1;DNA-directed RNA polymerase II subunit A;DNA-directed RNA polymerase III largest subunit;RNA-directed RNA polymerase II subunit RPB1
Organism-1
Human
基因ID-1
5430
SwissProt-1
P24928
Organism-2
Mouse
基因ID-2
20020
SwissProt-2
P08775
背景
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus





