- 产品信息
商品描述
靶点-Target
Mfn2
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
86kD
MW(Observed)
86kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0529R
特异性
Endogenous
基因名称
MFN2
蛋白名称
Mitofusin-2
别名
MFN2;CPRP1;KIAA0214;Mitofusin-2;Transmembrane GTPase MFN2
Organism-1
Human
基因ID-1
9927
SwissProt-1
O95140
Organism-2
Mouse
基因ID-2
170731
SwissProt-2
Q80U63
Organism-3
Rat
SwissProt-3
Q8R500
背景
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion outer membrane





