FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PUMA
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
21kD
MW(Observed)
21kD
推荐稀释比
IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0607R
特异性
Endogenous
基因名称
BBC3
蛋白名称
Bcl-2-binding component 3
别名
BBC3;PUMA;Bcl-2-binding component 3;JFY-1;p53 up-regulated modulator of apoptosis
Organism-1
Human
基因ID-1
27113
SwissProt-1
Q9BXH1
Organism-2
Mouse
基因ID-2
170770
SwissProt-2
Q99ML1
Organism-3
Rat
基因ID-3
317673
SwissProt-3
Q80ZG6
背景
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
细胞定位
Mitochondrion
