Acetyl Coenzyme A Carboxylase beta Rabbit mAb

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¥880.00

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产品规格:
  • 50μL
货号:

FAB2621252

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商品描述
  • 靶点-Target

    ACC-beta

  • 反应性

    Human,Mouse,Rat,

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    227kD

  • MW(Observed)

    265kD

  • 推荐稀释比

    IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0598R

  • 特异性

    Endogenous

  • 基因名称

    ACACB;ACC2;ACCB

  • 蛋白名称

    Acetyl-CoA carboxylase 2;ACC-beta;

  • 别名

    ACACB,Acetyl CoA carboxylase 2,ACC beta,ACC2,ACCB,AcetylCoA carboxylase 2,ACCbeta,ACCβ,ACC β,

  • Organism-1

    Human

  • 基因ID-1

    32

  • SwissProt-1

    O00763

  • 背景

    Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Mitochondrion