FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HDAC4
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
119kD
MW(Observed)
140kD
推荐稀释比
IHC 1:50-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0600R
特异性
Endogenous
基因名称
HDAC4
蛋白名称
Histone deacetylase 4
别名
HDAC4;KIAA0288;Histone deacetylase 4;HD4
Organism-1
Human
基因ID-1
9759
SwissProt-1
P56524
Organism-2
Mouse
基因ID-2
208727
SwissProt-2
Q6NZM9
Organism-3
Rat
基因ID-3
363287
SwissProt-3
Q99P99
背景
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Nucleus
