FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SH-PTP2
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
68kD
MW(Observed)
68kD
推荐稀释比
IHC 1:2000-1:8000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0592R
特异性
Endogenous
基因名称
PTPN11
蛋白名称
Tyrosine-protein phosphatase non-receptor type 11
别名
PTPN11;PTP2C;SHPTP2;Tyrosine-protein phosphatase non-receptor type 11;Protein-tyrosine phosphatase 1D;PTP-1D;Protein-tyrosine phosphatase 2C;PTP-2C;SH-PTP2;SHP-2;Shp2;SH-PTP3
Organism-1
Human
基因ID-1
5781
SwissProt-1
Q06124
Organism-2
Mouse
基因ID-2
19247
SwissProt-2
P35235
Organism-3
Rat
基因ID-3
25622
SwissProt-3
P41499
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016],
细胞定位
Cytoplasm, Nucleus
