- 产品信息
商品描述
靶点-Target
PAX6
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
47kD
MW(Observed)
47kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0618R
特异性
Endogenous
基因名称
PAX6 AN2
蛋白名称
PAX6
别名
Paired box protein Pax-6;Aniridia type II protein;Oculorhombin;
Organism-1
Human
基因ID-1
5080
SwissProt-1
P26367
Organism-2
Mouse
基因ID-2
18508
SwissProt-2
P63015
Organism-3
Rat
基因ID-3
25509
SwissProt-3
P63016
背景
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],
细胞定位
Nucleus





