FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GCSc-γ
反应性
Human,Mouse,Rat,
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
73kD
MW(Observed)
73kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0611R
特异性
Endogenous
基因名称
GCLC
蛋白名称
Glutamate--cysteine ligase catalytic subunit
别名
GCLC;GLCL;GLCLC;Glutamate--cysteine ligase catalytic subunit;GCS heavy chain;Gamma-ECS;Gamma-glutamylcysteine synthetase
Organism-1
Human
基因ID-1
2729
SwissProt-1
P48506
Organism-2
Mouse
基因ID-2
14629
SwissProt-2
P97494
Organism-3
Rat
基因ID-3
25283
SwissProt-3
P19468
背景
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010],
细胞定位
Cytoplasm
