FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SRP72
反应性
Human
应用
WB,IHC,IF,ICC,FC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
74kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0811R
特异性
Endogenous
基因名称
SRP72
蛋白名称
Signal recognition particle subunit SRP72;SRP72;Signal recognition particle 72 kDa protein;
别名
SRP72;Signal recognition particle subunit SRP72 ;SRP72;Signal recognition particle 72 kDa protein;
Organism-1
Human
基因ID-1
6731
SwissProt-1
O76094
背景
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
细胞定位
Cytoplasm. Endoplasmic reticulum.
