FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
STARD4
反应性
Human
应用
WB,IF,ICC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:1000-5000;ICC/IF 1:100-300
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0810R
特异性
Endogenous
基因名称
STARD4
蛋白名称
StAR-related lipid transfer protein 4;START domain-containing protein 4;StARD4;
别名
STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4;
Organism-1
Human
基因ID-1
134429
SwissProt-1
Q96DR4
背景
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
