FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NDUFA1
反应性
Human
应用
WB,IHC,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
8kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;IP 1:50-100
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0806R
特异性
Endogenous
基因名称
NDUFA1
蛋白名称
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit;
别名
NDUFA1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit;
Organism-1
Human
基因ID-1
4694
SwissProt-1
O15239
背景
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
