- 产品信息
商品描述
靶点-Target
UPB1
反应性
Human
应用
WB,IHC,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;IP 1:50-100
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0799R
特异性
Endogenous
基因名称
UPB1;BUP1
蛋白名称
Beta-ureidopropionase;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase;
别名
UPB1;BUP1;Beta-ureidopropionase ;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase;
Organism-1
Human
基因ID-1
51733
SwissProt-1
Q9UBR1
Organism-2
Mouse
基因ID-2
103149
SwissProt-2
Q8VC97
Organism-3
Rat
基因ID-3
116593
SwissProt-3
Q03248
背景
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
细胞定位
Cytoplasm.





