- 产品信息
商品描述
靶点-Target
ASPP2
反应性
Human
应用
WB,IHC,IF,ICC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
124kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0791R
特异性
Endogenous
基因名称
TP53BP2;ASPP2;BBP
蛋白名称
Apoptosis-stimulating of p53 protein 2;Bcl2-binding protein;Bbp;Renal carcinoma antigen NY-REN-51;Tumor suppressor p53-binding protein 2;53BP2;p53-binding protein 2;p53BP2;
别名
TP53BP2;ASPP2;BBP;Apoptosis-stimulating of p53 protein 2 ;Bcl2-binding protein;Bbp;Renal carcinoma antigen NY-REN-51;Tumor suppressor p53-binding protein 2;53BP2;p53-binding protein 2;p53BP2;
Organism-1
Human
基因ID-1
7159
SwissProt-1
Q13625
Organism-2
Mouse
SwissProt-2
Q8CG79
背景
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, perinuclear region. Nucleus. Note=Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.





