- 产品信息
商品描述
靶点-Target
ACTY
反应性
Human
应用
WB,IHC,IF,ICC,FC,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
41kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0778R
特异性
Endogenous
基因名称
ACTR1B;CTRN2
蛋白名称
Beta-centractin;Actin-related protein 1B;ARP1B;
别名
ACTR1B;CTRN2;Beta-centractin ;Actin-related protein 1B;ARP1B;
Organism-1
Human
基因ID-1
10120
SwissProt-1
P42025
Organism-2
Mouse
基因ID-2
226977
SwissProt-2
Q8R5C5
背景
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],
细胞定位
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.





