FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD89
反应性
Human
应用
WB,IHC,IF,ICC,FC,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0770R
特异性
Endogenous
基因名称
FCAR;CD89
蛋白名称
Immunoglobulin alpha Fc receptor;IgA Fc receptor;CD antigen CD89;
别名
FCAR;CD89;Immunoglobulin alpha Fc receptor ;IgA Fc receptor;CD antigen CD89;
Organism-1
Human
基因ID-1
2204
SwissProt-1
P24071
背景
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; [Isoform B]: Secreted.; [Isoform B-delta-S2]: Secreted.
