Estrogen Receptor α Rabbit mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621172

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商品描述
  • 靶点-Target

    ESR1

  • 反应性

    Human,Mouse,Rat,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    66kD

  • MW(Observed)

    66kD

  • 推荐稀释比

    IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0632R

  • 特异性

    Endogenous

  • 基因名称

    Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

  • 蛋白名称

    Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

  • 别名

    ESR1 ESR NR3A1

  • Organism-1

    Human

  • 基因ID-1

    2099

  • SwissProt-1

    P03372

  • Organism-2

    Mouse

  • 基因ID-2

    13982

  • SwissProt-2

    P19785

  • Organism-3

    Rat

  • 基因ID-3

    24890

  • SwissProt-3

    P06211

  • 背景

    estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],

  • 细胞定位

    Nucleus