FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Stat6
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
94kD
MW(Observed)
110kD
推荐稀释比
IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0623R
特异性
Endogenous
基因名称
STAT6
蛋白名称
Signal transducer and activator of transcription 6
别名
STAT6;Signal transducer and activator of transcription 6;IL-4 Stat
Organism-1
Human
基因ID-1
6778
SwissProt-1
P42226
Organism-2
Mouse
基因ID-2
20852
SwissProt-2
P52633
背景
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
细胞定位
Nucleus
