Erk 1/2 (Phospho Thr202/Tyr204) Rabbit mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2621150
- 产品信息
商品描述
靶点-Target
ERK 1/2
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Thr202/Tyr204
MW(Calculated)
44kD,42kD
MW(Observed)
44kD,42kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0643R
特异性
This antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), and Erk2 singly phosphorylated at Thr185, and Erk1 singly phosphorylated at Thr202
基因名称
MAPK1/MAPK3
蛋白名称
Mitogen-activated protein kinase 3
别名
MAPK3;ERK1;PRKM3;Mitogen-activated protein kinase 3;MAP kinase 3;MAPK 3;ERT2;Extracellular signal-regulated kinase 1;ERK-1;Insulin-stimulated MAP2 kinase;MAP kinase isoform p44;p44-MAPK;Microtubule-associated protein 2 kinase;p
Organism-1
Human
基因ID-1
5594;5595
SwissProt-1
P27361;P28482
Organism-2
Mouse
基因ID-2
26417;26413
Organism-3
Rat
基因ID-3
50689;116590
SwissProt-3
P21708;P63086
背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Nucleus





