- 产品信息
商品描述
靶点-Target
Bmi-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
48kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0715R
特异性
Endogenous
基因名称
PAX8
蛋白名称
PAX-8
别名
Paired box protein Pax-8
Organism-1
Human
基因ID-1
7849
SwissProt-1
Q06710
Organism-2
Mouse
基因ID-2
18510
SwissProt-2
Q00288
Organism-3
Rat
基因ID-3
81819
SwissProt-3
P51974
背景
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
细胞定位
Nucleus





