- 产品信息
商品描述
靶点-Target
NRF-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
54kD
MW(Observed)
68kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0704R
特异性
Endogenous
基因名称
NRF1
蛋白名称
Nuclear respiratory factor 1
别名
NRF1;Nuclear respiratory factor 1;NRF-1;Alpha palindromic-binding protein;Alpha-pal
Organism-1
Human
基因ID-1
4899
SwissProt-1
Q16656
Organism-2
Mouse
基因ID-2
18181
SwissProt-2
Q9WU00
Organism-3
Rat
SwissProt-3
Q62792
背景
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],
细胞定位
Nucleus





