IκB-α Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621121

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商品描述
  • 靶点-Target

    IκB-α

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    36kD

  • MW(Observed)

    36kD

  • 推荐稀释比

    IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0702R

  • 特异性

    Endogenous

  • 基因名称

    NFKBIA IKBA MAD3 NFKBI

  • 蛋白名称

    NF-kappa-B inhibitor alpha

  • 别名

    NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;

  • Organism-1

    Human

  • 基因ID-1

    4792

  • SwissProt-1

    P25963

  • Organism-2

    Mouse

  • 基因ID-2

    18035

  • SwissProt-2

    Q9Z1E3

  • Organism-3

    Rat

  • 基因ID-3

    25493

  • SwissProt-3

    Q63746

  • 背景

    This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],

  • 细胞定位

    Cytoplasm, Nucleus