IL-1 β Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621111

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商品描述
  • 靶点-Target

    IL-1β

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    31kD

  • MW(Observed)

    31kD

  • 推荐稀释比

    WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0689R

  • 特异性

    Endogenous

  • 基因名称

    IL1B IL1F2

  • 蛋白名称

    Interleukin-1 beta (IL-1 beta) (Catabolin)

  • 别名

    Interleukin-1 beta;IL-1 beta;Catabolin;

  • Organism-1

    Human

  • 基因ID-1

    3553

  • SwissProt-1

    P01584

  • Organism-2

    Mouse

  • 基因ID-2

    16176

  • SwissProt-2

    P10749

  • Organism-3

    Rat

  • SwissProt-3

    Q63264

  • 背景

    interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Secreted