FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Insulin R
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
95kD
MW(Observed)
95kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0688R
特异性
Endogenous
基因名称
INSR
蛋白名称
Insulin Receptor β (Tyr1345)
别名
Insulin receptor;IR;CD antigen CD220;[Cleaved into: Insulin receptor subunit alpha;Insulin receptor subunit beta]
Organism-1
Human
基因ID-1
3643
SwissProt-1
P06213
Organism-2
Mouse
基因ID-2
16337
SwissProt-2
P15208
Organism-3
Rat
SwissProt-3
P15127
背景
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
细胞定位
Membrane
