BACE Rabbit mAb

活动价:

¥1680.00

市场价:¥2400.00

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产品规格:
  • 100ul
货号:

FAB2621104

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商品描述
  • 靶点-Target

    BACE

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    56kD

  • MW(Observed)

    70kD

  • 推荐稀释比

    IHC 1:100-1:400;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0655R

  • 特异性

    Endogenous

  • 基因名称

    BACE1

  • 蛋白名称

    Beta-secretase 1

  • 别名

    BACE1;BACE;KIAA1149;Beta-secretase 1;Aspartyl protease 2;ASP2;Asp 2;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;Memapsin-2;Membrane-associated aspartic protease 2

  • Organism-1

    Human

  • 基因ID-1

    23621

  • SwissProt-1

    P56817

  • Organism-2

    Mouse

  • 基因ID-2

    23821

  • SwissProt-2

    P56818

  • Organism-3

    Rat

  • 基因ID-3

    29392

  • SwissProt-3

    P56819

  • 背景

    beta-secretase 1(BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015],

  • 细胞定位

    Membrane, Cytoplasm