- 产品信息
商品描述
靶点-Target
Mcl-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
37kD
MW(Observed)
37kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0585R
特异性
Endogenous
基因名称
MCL1
蛋白名称
Induced myeloid leukemia cell differentiation protein Mcl-1
别名
MCL1;BCL2L3;Induced myeloid leukemia cell differentiation protein Mcl-1;Bcl-2-like protein 3;Bcl2-L-3;Bcl-2-related protein EAT/mcl1;mcl1/EAT
Organism-1
Human
基因ID-1
4170
SwissProt-1
Q07820
Organism-2
Mouse
基因ID-2
17210
SwissProt-2
P97287
Organism-3
Rat
基因ID-3
60430
SwissProt-3
Q9Z1P3
背景
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],
细胞定位
Cytoplasm, Nucleus





