FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP1α/β
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
38kD
MW(Observed)
38kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0691R
特异性
Endogenous
基因名称
PPP1CA;PPP1CB
蛋白名称
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;
别名
PPP1CA;PPP1A;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;PP-1A;PPP1CB;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;PP-1B;PPP1CD;
Organism-1
Human
基因ID-1
5500;5499
SwissProt-1
P62136;P62140
Organism-2
Mouse
基因ID-2
19045;19046
SwissProt-2
P62137;P62141
Organism-3
Rat
基因ID-3
24668;25594
SwissProt-3
P62138;P62142
背景
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Nucleus
