- 产品信息
商品描述
靶点-Target
CPT1A
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
88kD
MW(Observed)
88kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0640R
特异性
Endogenous
基因名称
CPT1A CPT1
蛋白名称
CPT1A
别名
Carnitine O-palmitoyltransferase 1, liver isoform;CPT1-L;Carnitine O-palmitoyltransferase I, liver isoform;CPT I;CPTI-L;Carnitine palmitoyltransferase 1A;
Organism-1
Human
基因ID-1
1374
SwissProt-1
P50416
Organism-2
Mouse
基因ID-2
12894
SwissProt-2
P97742
Organism-3
Rat
基因ID-3
25757
SwissProt-3
P32198
背景
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion outer membrane





