- 产品信息
商品描述
靶点-Target
JAK1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
133kD
MW(Observed)
133kD
推荐稀释比
IHC 1:100-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0658R
特异性
Endogenous
基因名称
JAK1 JAK1A JAK1B
蛋白名称
JAK1
别名
Tyrosine-protein kinase JAK1;Janus kinase 1;JAK-1;
Organism-1
Human
基因ID-1
3716
SwissProt-1
P23458
Organism-2
Mouse
SwissProt-2
P52332
背景
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.





