PRAS40 (Phospho Thr246) Rabbit mAb

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产品规格:
  • 100ul
货号:

FAB2621073

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商品描述
  • 靶点-Target

    PRAS40

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Phospho

  • 修饰-Modification

    Thr246

  • MW(Calculated)

    27kD

  • MW(Observed)

    40kD

  • 推荐稀释比

    IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0756R

  • 特异性

    Phospho-PRAS40 (T246) Polyclonal Antibody detects endogenous levels of PRAS40 protein only when phosphorylated at T246.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LNtSD

  • 基因名称

    AKT1S1

  • 蛋白名称

    Proline-rich AKT1 substrate 1

  • 别名

    AKT1S1;PRAS40;Proline-rich AKT1 substrate 1;40 kDa proline-rich AKT substrate

  • Organism-1

    Human

  • 基因ID-1

    84335

  • SwissProt-1

    Q96B36

  • Organism-2

    Mouse

  • 基因ID-2

    67605

  • SwissProt-2

    Q9D1F4

  • 背景

    AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],

  • 细胞定位

    Cytoplasm, cytosol . Found in the cytosolic fraction of the brain. .