FGF-2 Polyclonal Antibody
¥680.00
RPS6 (Phospho Ser240/Ser244) Rabbit mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2621064
- 产品信息
商品描述
靶点-Target
Ribosomal Protein S6
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser240/244
MW(Calculated)
29kD
MW(Observed)
29kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0447R
特异性
This antibody detects endogenous levels of Ribosomal Protein S6 only when phosphorylated at Ser240 or Ser244.
基因名称
RPS6
蛋白名称
40S ribosomal protein S6
别名
RPS6;OK/SW-cl.2;40S ribosomal protein S6;Phosphoprotein NP33
Organism-1
Human
基因ID-1
6194
SwissProt-1
P62753
Organism-2
Mouse
基因ID-2
20104
SwissProt-2
P62754
Organism-3
Rat
基因ID-3
29304
SwissProt-3
P62755
背景
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed
细胞定位
nucleus,nucleoplasm,nucleolus,cytoplasm,cytosol,ribosome,polysome,small ribosomal subunit,membrane,cytosolic small ribosomal subunit,dendrite,intracellular ribonucleoprotein complex,cytoplasmic ribonucleoprotein granu
