- 产品信息
商品描述
靶点-Target
Caspase 6
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
33kD
MW(Observed)
33kD
推荐稀释比
IHC 1:200-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0513R
特异性
Endogenous
基因名称
CASP6
蛋白名称
Caspase6
别名
CASP6;MCH2;Caspase-6;CASP-6;Apoptotic protease Mch-2
Organism-1
Human
基因ID-1
839
SwissProt-1
P55212
Organism-2
Mouse
基因ID-2
12368
SwissProt-2
O08738
Organism-3
Rat
SwissProt-3
O35397
背景
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015],
细胞定位
Cytoplasm . Nucleus .





