- 产品信息
商品描述
靶点-Target
DARPP-32
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
23kD
MW(Observed)
32kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0500R
特异性
Endogenous
基因名称
PPP1R1B
蛋白名称
Protein phosphatase 1 regulatory subunit 1B
别名
PPP1R1B;DARPP32;Protein phosphatase 1 regulatory subunit 1B;DARPP-32;Dopamine- and cAMP-regulated neuronal phosphoprotein
Organism-1
Human
基因ID-1
84152
SwissProt-1
Q9UD71
Organism-2
Mouse
基因ID-2
19049
SwissProt-2
Q60829
Organism-3
Rat
基因ID-3
360616
SwissProt-3
Q6J4I0
背景
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm.





