DRP1 (Phospho Ser616) Rabbit mAb

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¥1680.00

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产品规格:
  • 100ul
货号:

FAB2621034

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商品描述
  • 靶点-Target

    DRP1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Phospho

  • 修饰-Modification

    Ser616

  • MW(Calculated)

    82kD

  • MW(Observed)

    82kD

  • 推荐稀释比

    WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0754R

  • 特异性

    Detects endogenous levels of DRP1 only when phosphorylated at Ser616(human,mouse), Ser637(Rat). The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PAsPQ

  • 基因名称

    DNM1L

  • 蛋白名称

    Dynamin-1-like protein

  • 别名

    DNM1L;DLP1;DRP1;Dynamin-1-like protein;Dnm1p/Vps1p-like protein;DVLP;Dynamin family member proline-rich carboxyl-terminal domain less;Dymple;Dynamin-like protein;Dynamin-like protein 4;Dynamin-like protein IV;HdynIV;Dynamin-rela

  • Organism-1

    Human

  • 基因ID-1

    10059

  • SwissProt-1

    O00429

  • Organism-2

    Mouse

  • 基因ID-2

    74006

  • SwissProt-2

    Q8K1M6

  • Organism-3

    Rat

  • 基因ID-3

    114114

  • SwissProt-3

    O35303

  • 背景

    This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],

  • 细胞定位

    Cytoplasm