DRP1 (Phospho Ser616) Rabbit mAb
活动价:
市场价:¥2400.00
- 100ul
FAB2621034
- 产品信息
商品描述
靶点-Target
DRP1
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser616
MW(Calculated)
82kD
MW(Observed)
82kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0754R
特异性
Detects endogenous levels of DRP1 only when phosphorylated at Ser616(human,mouse), Ser637(Rat). The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PAsPQ
基因名称
DNM1L
蛋白名称
Dynamin-1-like protein
别名
DNM1L;DLP1;DRP1;Dynamin-1-like protein;Dnm1p/Vps1p-like protein;DVLP;Dynamin family member proline-rich carboxyl-terminal domain less;Dymple;Dynamin-like protein;Dynamin-like protein 4;Dynamin-like protein IV;HdynIV;Dynamin-rela
Organism-1
Human
基因ID-1
10059
SwissProt-1
O00429
Organism-2
Mouse
基因ID-2
74006
SwissProt-2
Q8K1M6
Organism-3
Rat
基因ID-3
114114
SwissProt-3
O35303
背景
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],
细胞定位
Cytoplasm





