FGF-2 Polyclonal Antibody
¥680.00
Syk (Phospho Tyr525/526) Rabbit mAb
活动价：
¥1680.00
市场价：¥2400.00
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产品规格：
- 100ul
货号：
FAB2621021
- 产品信息
商品描述
靶点-Target
Syk
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Tyr525/526
MW(Calculated)
72kD
MW(Observed)
72kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0753R
特异性
Antibody detects endogenous levels of syk protein only when phosphorylated at Tyr525/526 of human Syk or Tyr519/520 of mouse Syk. It also detects Syk protein when singly phosphorylated at Tyr526 of human Syk or Tyr520 of mouse Syk. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): ENyyKA
基因名称
SYK
蛋白名称
Tyrosine-protein kinase SYK
别名
SYK;Tyrosine-protein kinase SYK;Spleen tyrosine kinase;p72-Syk
Organism-1
Human
基因ID-1
6850
SwissProt-1
P43405
Organism-2
Mouse
基因ID-2
20963
SwissProt-2
P48025
Organism-3
Rat
基因ID-3
25155
SwissProt-3
Q64725
背景
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
细胞定位
Cell membrane . Cytoplasm, cytosol .
