FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HDAC6
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
131kD
MW(Observed)
160kD
推荐稀释比
IHC 1:2000-1:10000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0826R
特异性
Endogenous
基因名称
HDAC6
蛋白名称
Histone deacetylase 6
别名
HDAC6;KIAA0901;JM21;Histone deacetylase 6;HD6
Organism-1
Human
基因ID-1
10013
SwissProt-1
Q9UBN7
Organism-2
Mouse
基因ID-2
15185
SwissProt-2
Q9Z2V5
背景
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus . Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules. .
