CREB-1 (Phospho Ser133) Rabbit mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2621013
- 产品信息
商品描述
靶点-Target
CREB-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser133
MW(Calculated)
37kD
MW(Observed)
43kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0863R
特异性
Phospho-CREB-1 (S133) Antibody detects endogenous levels of CREB-1 protein only when phosphorylated at S133.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RPsYR
基因名称
CREB1
蛋白名称
Cyclic AMP-responsive element-binding protein 1
别名
CREB1;Cyclic AMP-responsive element-binding protein 1;CREB-1;cAMP-responsive element-binding protein 1
Organism-1
Human
基因ID-1
1385
SwissProt-1
P16220
Organism-2
Mouse
基因ID-2
12912
SwissProt-2
Q01147
Organism-3
Rat
基因ID-3
81646
SwissProt-3
P15337
背景
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],
细胞定位
Nucleus .





