CREB-1 (Phospho Ser133) Rabbit mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621013

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商品描述
  • 靶点-Target

    CREB-1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Phospho

  • 修饰-Modification

    Ser133

  • MW(Calculated)

    37kD

  • MW(Observed)

    43kD

  • 推荐稀释比

    IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0863R

  • 特异性

    Phospho-CREB-1 (S133) Antibody detects endogenous levels of CREB-1 protein only when phosphorylated at S133.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RPsYR

  • 基因名称

    CREB1

  • 蛋白名称

    Cyclic AMP-responsive element-binding protein 1

  • 别名

    CREB1;Cyclic AMP-responsive element-binding protein 1;CREB-1;cAMP-responsive element-binding protein 1

  • Organism-1

    Human

  • 基因ID-1

    1385

  • SwissProt-1

    P16220

  • Organism-2

    Mouse

  • 基因ID-2

    12912

  • SwissProt-2

    Q01147

  • Organism-3

    Rat

  • 基因ID-3

    81646

  • SwissProt-3

    P15337

  • 背景

    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Nucleus .