- 产品信息
商品描述
靶点-Target
Claudin 3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
23kD
MW(Observed)
20kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0850R
特异性
Endogenous
基因名称
CLDN3 C7orf1 CPETR2
蛋白名称
C7orf1;Claudin-3;Claudin3;CLD3_HUMAN;CLDN 3;Cldn3;Clostridium perfringens enterotoxin receptor 2;CPE R2;CPE receptor 2;CPE-R 2;CPE-receptor 2;CPETR 2;CPETR2;HRVP 1;HRVP1;Rat ventral prostate 1 like protein;Rat ventral prostate.1 protein homolog;RVP1;Ventral prostate.1 like protein;Ventral prostate.1 protein homolog
别名
C7orf1;Claudin-3;Claudin3;CLD3_HUMAN;CLDN 3;Cldn3;Clostridium perfringens enterotoxin receptor 2;CPE R2;CPE receptor 2;CPE-R 2;CPE-receptor 2;CPETR 2;CPETR2;HRVP 1;HRVP1;Rat ventral prostate 1 like protein;Rat ventral prostate.1 protein homolog;RVP1;Ventral prostate.1 like protein;Ventral prostate.1 protein homolog
Organism-1
Human
基因ID-1
1365
SwissProt-1
O15551
Organism-2
Mouse
SwissProt-2
Q9Z0G9
Organism-3
Rat
SwissProt-3
Q63400
背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],
细胞定位
Membranous





