- 产品信息
商品描述
靶点-Target
IRF 1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
37kD
MW(Observed)
48kD
推荐稀释比
IHC 1:100-1:400;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0828R
特异性
Endogenous
基因名称
IRF1
蛋白名称
Interferon regulatory factor 1
别名
IRF1;Interferon regulatory factor 1;IRF-1
Organism-1
Human
基因ID-1
3659
SwissProt-1
P10914
Organism-2
Mouse
基因ID-2
16362
SwissProt-2
P15314
Organism-3
Rat
基因ID-3
24508
SwissProt-3
P23570
背景
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. .





