Cleaved Caspase-7 (Asp198) Rabbit mAb

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产品规格:
  • 100ul
货号:

FAB2620983

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商品描述
  • 靶点-Target

    Caspase 7

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    34kD

  • MW(Observed)

    18kD

  • 推荐稀释比

    WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0879R

  • 特异性

    Cleaved Caspase-7 (Asp198) Antibody detects endogenous levels of Cleaved Caspase-7 protein only when phosphorylated at Asp198.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QAdSG

  • 基因名称

    CASP7

  • 蛋白名称

    Caspase7

  • 别名

    CASP7;MCH3;Caspase-7;CASP-7;Apoptotic protease Mch-3;CMH-1;ICE-like apoptotic protease 3;ICE-LAP3

  • Organism-1

    Human

  • 基因ID-1

    840

  • SwissProt-1

    P55210

  • Organism-2

    Mouse

  • 基因ID-2

    12369

  • SwissProt-2

    P97864

  • 背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

  • 细胞定位

    Cytoplasm.