Cleaved Caspase-7 (Asp198) Rabbit mAb
活动价:
市场价:¥2400.00
- 100ul
FAB2620983
- 产品信息
商品描述
靶点-Target
Caspase 7
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
34kD
MW(Observed)
18kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0879R
特异性
Cleaved Caspase-7 (Asp198) Antibody detects endogenous levels of Cleaved Caspase-7 protein only when phosphorylated at Asp198.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QAdSG
基因名称
CASP7
蛋白名称
Caspase7
别名
CASP7;MCH3;Caspase-7;CASP-7;Apoptotic protease Mch-3;CMH-1;ICE-like apoptotic protease 3;ICE-LAP3
Organism-1
Human
基因ID-1
840
SwissProt-1
P55210
Organism-2
Mouse
基因ID-2
12369
SwissProt-2
P97864
背景
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
细胞定位
Cytoplasm.





