FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NMDARA2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
161kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NMDARA2
特异性
This antibody detects endogenous levels of NMDARA2 at Human, Mouse,Rat
基因名称
GRIN2A NMDAR2A
蛋白名称
NMDARA2
别名
Glutamate [NMDA] receptor subunit epsilon-1;N-methyl D-aspartate receptor subtype 2A;NMDAR2A;NR2A;hNR2A;
Organism-1
Human
基因ID-1
2903
SwissProt-1
Q12879
Organism-2
Mouse
基因ID-2
14811
SwissProt-2
P35436
Organism-3
Rat
基因ID-3
24409
SwissProt-3
Q00959
背景
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Cell projection, dendritic spine . Cell membrane ; Multi-pass membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Expression at the dendrite cell membrane and at synapses is regulated by SORCS2 and the retromer complex. .
