FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PDE4D
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
isform D3:76kD,isform D4:91kD,isform D1/D2:66kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDE4D
特异性
This antibody detects endogenous levels of PDE4D at Human, Mouse,Rat
基因名称
PDE4D DPDE3
蛋白名称
PDE4D
别名
cAMP-specific 3',5'-cyclic phosphodiesterase 4D;DPDE3;PDE43;
Organism-1
Human
基因ID-1
5144
SwissProt-1
Q08499
Organism-2
Mouse
基因ID-2
238871
SwissProt-2
Q01063
Organism-3
Rat
基因ID-3
24627
SwissProt-3
P14270
背景
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009],
细胞定位
Apical cell membrane . Cytoplasm . Membrane . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells. .
