- 产品信息
商品描述
靶点-Target
DYRK2/4
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DYRK2/4
特异性
This antibody detects endogenous levels of DYRK2/4 at Human, Mouse,Rat
基因名称
DYRK2
蛋白名称
DYRK2/4
别名
Dual specificity tyrosine-phosphorylation-regulated kinase 2;
Organism-1
Human
基因ID-1
8445
SwissProt-1
Q92630
Organism-2
Mouse
基因ID-2
69181
SwissProt-2
Q5U4C9
背景
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Translocates into the nucleus following DNA damage.





