ROR1 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619570

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商品描述
  • 靶点-Target

    ROR1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    105kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human ROR1

  • 特异性

    This antibody detects endogenous levels of ROR1 at Human, Mouse,Rat

  • 基因名称

    ROR1 NTRKR1

  • 蛋白名称

    ROR1

  • 别名

    Tyrosine-protein kinase transmembrane receptor ROR1;Neurotrophic tyrosine kinase, receptor-related 1;

  • Organism-1

    Human

  • 基因ID-1

    4919

  • SwissProt-1

    Q01973

  • Organism-2

    Mouse

  • 基因ID-2

    26563

  • SwissProt-2

    Q9Z139

  • 背景

    This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012],

  • 细胞定位

    Membrane ; Single-pass type I membrane protein. Cell projection, axon .