- 产品信息
商品描述
靶点-Target
ROR1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ROR1
特异性
This antibody detects endogenous levels of ROR1 at Human, Mouse,Rat
基因名称
ROR1 NTRKR1
蛋白名称
ROR1
别名
Tyrosine-protein kinase transmembrane receptor ROR1;Neurotrophic tyrosine kinase, receptor-related 1;
Organism-1
Human
基因ID-1
4919
SwissProt-1
Q01973
Organism-2
Mouse
基因ID-2
26563
SwissProt-2
Q9Z139
背景
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012],
细胞定位
Membrane ; Single-pass type I membrane protein. Cell projection, axon .





