VR1 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619568

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商品描述
  • 靶点-Target

    VR1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    92kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human VR1

  • 特异性

    This antibody detects endogenous levels of VR1 at Human, Mouse,Rat

  • 基因名称

    TRPV1 VR1

  • 蛋白名称

    VR1

  • 别名

    Transient receptor potential cation channel subfamily V member 1;TrpV1;Capsaicin receptor;Osm-9-like TRP channel 1;OTRPC1;Vanilloid receptor 1;

  • Organism-1

    Human

  • 基因ID-1

    7442

  • SwissProt-1

    Q8NER1

  • Organism-2

    Mouse

  • 基因ID-2

    193034

  • SwissProt-2

    Q704Y3

  • Organism-3

    Rat

  • 基因ID-3

    83810

  • SwissProt-3

    O35433

  • 背景

    transient receptor potential cation channel subfamily V member 1(TRPV1) Homo sapiens Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendritic spine membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Mostly, but not exclusively expressed in postsynaptic dendritic spines. .