- 产品信息
商品描述
靶点-Target
RFA1
反应性
Human,Monkey,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
68kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RFA1
特异性
This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1
基因名称
RPA1 REPA1 RPA70
蛋白名称
RFA1
别名
Replication protein A 70 kDa DNA-binding subunit;RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein;
Organism-1
Human
基因ID-1
6117
SwissProt-1
P27694
Organism-2
Mouse
基因ID-2
68275
SwissProt-2
Q8VEE4
背景
function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
细胞定位
Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .





